Category: news

Dr. Aseem Malhotra Promoted Covid-19 Vaccine on TV, Now Says “Stop!”

The Journal of Insulin Resistance has published In a two-part research paper entitled “ Curing the pandemic of misinformation on COVID-19 mRNA vaccines through real evidence-based medicine,”

This was written by one of UK’s most eminent Cardiologists Dr. Aseem Malhotra, who was one of the first to take two doses of the vaccine and promote it on @Good Morning Britain says that since the rollout of the vaccine the evidence of its effectiveness and true rates of adverse events have changed.

Furthermore, real-world data reveals that in the non-elderly population, the number needed to vaccinate to prevent one death from Covid-19 runs into thousands and that re-analysis of randomized controlled trial data from the initial vaccine clinical trials suggests a greater risk of suffering a serious adverse event from the vaccine than to be hospitalized with Covid-19.

Ministry of Health or Ministry of Deceits

Listen to Concerned Doctors latest podcast below: As the new booster, or as the Biden administration calls it, the ‘updated vaccine’ rolled out with a glossy White House press conference in the past week, the obvious question is when do our public health authorities take an inventory of the good, bad and the downright deadly…

SARS-CoV-2 Spike Proteins and Cell-Cell Communication Inhibits TFPI and Induces Thrombogenic Factos in Human Lung Microvascular Endothelial Cell and Neutrophils: Implications for COVID-19 Coagulopathy Pathogenisis

In SARS-CoV-2-infected humans, disease progression is often associated with acute respiratory distress syndrome involving severe lung injury, coagulopathy, and thrombosis of the alveolar capillaries. The pathogenesis of these pulmonary complications in COVID-19 patients has not been elucidated. Autopsy study of these patients showed SARS-CoV-2 virions in pulmonary vessels and sequestrated leukocytes infiltrates associated with endotheliopathy and microvascular thrombosis. Since SARS-CoV-2 enters and infects target cells by binding its spike (S) protein to cellular angiotensin-converting enzyme 2 (ACE2), and there is evidence that vascular endothelial cells and neutrophils express ACE2, we investigated the effect of S-proteins and cell–cell communication on primary human lung microvascular endothelial cells (HLMEC) and neutrophils expression of thrombogenic factors and the potential mechanisms. Using S-proteins of two different SARS-CoV-2 variants (Wuhan and Delta), we demonstrate that exposure of HLMEC or neutrophils to S-proteins, co-culture of HLMEC exposed to S-proteins with non-exposed neutrophils, or co-culture of neutrophils exposed to S-proteins with non-exposed HLMEC induced transcriptional upregulation of tissue factor (TF), significantly increased the expression and secretion of factor (F)-V, thrombin, and fibrinogen and inhibited tissue factor pathway inhibitor (TFPI), the primary regulator of the extrinsic pathway of blood coagulation, in both cell types. Recombinant (r)TFPI and a thiol blocker (5,5′-dithio-bis-(2-nitrobenzoic acid)) prevented S-protein-induced expression and secretion of Factor-V, thrombin, and fibrinogen. Thrombomodulin blocked S-protein-induced expression and secretion of fibrinogen but had no effect on S-protein-induced expression of Factor-V or thrombin. These results suggests that following SARS-CoV-2 contact with the pulmonary endothelium or neutrophils and endothelial–neutrophil interactions, viral S-proteins induce coagulopathy via the TF pathway and mechanisms involving functional thiol groups. These findings suggest that using rTFPI and/or thiol-based drugs could be a viable therapeutic strategy against SARS-CoV-2-induced coagulopathy and thrombosis. View Full-Text

Oro-Systemic Health Symposium 2022 – Part 3: Graham Lloyd-Jones – The anatomy of COVID-19

Dr. Graham Lloyd-Jones, Consultant Radiologist at Salisbury NHS Foundation Trust and Director of Radiology Masterclass, describes the nature of COVID-19 lung disease from the perspective of medical imaging. He proposes how understanding the lung disease leads to proposing a direct anatomical route of SARS-CoV-2 viral infection from the mouth to the lungs via the blood…